JUST READ THE INSTRUCTIONS

a genetic exploration by ernesto llano

  • started aligning the stand-in genome to grch38 so each read gets an address
  • created a codex skill to search X/Twitter through the xAI API
  • compared CPU Sarek vs NVIDIA Parabricks GPUs, but kept the first run simple
  • migrated the project to a new codex environment for cheaper tokens after spending too much
  • ran small google cloud and seqera tests to make sure the setup is working correctly
  • uploaded a 78 gb gzipped sample wgs genome file to google cloud to prepare the first sarek run
  • set up seqera and google cloud accounts so analysis can run off the local computer
  • built this site so the work log can be updated each day
  • ran nf-core/sarek on the cloud for the first time
  • set up an external ssd as the working home for genome data
  • extracted a 30x short-read whole genome from the personal genomes project onto that drive as a temporary sample
  • planned the analysis architecture around nf-core/sarek, the open source pipeline we will use first